Charlie in Lost died in a more peaceful way
Too bad his death was in vain and he didn't even know it. He thought he was being a major help to everyone.
Charlie in Heroes died a pretty useless death too. If anything, her death was a major blow to everyone. She died so someone could have her pretty much useless power. And then Hiro tried to go back in time to save her, but he found out she had cancer and was going to die anyway. Hiro blamed himself for her death and lost his powers for a little while when he could have been out helping people.